Peppermint oil: Indication, Dosage, Side Effect, Precaution

This information is not country-specific. Please refer to the Indonesia prescribing information.

Generic Medicine Info

Indications and Dosage

Oral
IBS (irritable bowel syndrome)

Adult: Each cap contains 0.2 mL peppermint oil: 1 cap tid, may increase to 2 cap tid. Max duration of treatment: 3 months.
Child: ≥15 year Same as adult dose.

Oral
Gastrointestinal tract spasm

Adult: 10-40 mL daily in 3-4 divided doses as necessary.
Child: >12 yr Same as adult dose.

Topical/Cutaneous
Pruritic skin disorders

Adult: As 0.3% soln: Apply and rub rapidly for 10 seconds onto affected area.
Child: ≥2 year Same as adult dose.

Transdermal
Topical analgesia

Adult: As 0.3% patch: Apply onto affected area up to 3 days, if desired.
Child: ≥10 yr Same as adult dose.

Special Precautions

Patient w/ GERD, GI inflammation/ulceration, biliary diseases (e.g. bile obstruction, cholangitis, gallstones), hiatal hernia. Childn. Pregnancy and lactation.

Adverse Reactions

Significant: Heartburn, perianal irritation, severe constipation, blood in faeces, difficulty or pain during urination, abnormal vag bleeding or discharge, wt loss, anorexia, fever.
Immunologic: Rarely, allergic reactions (manifested by headache, bradycardia, ataxia, tremor, anaphylactic shock, erythematous skin rash).

Overdosage

Symptoms: Severe nausea, vomiting, abdominal pain, vertigo, drowsiness, ataxia, coma. Management: Symptomatic and supportive treatment. Perform gastric lavage.

Drug Interactions

May interfere w/ the clearance of drugs which are mediated by CYP3A4 enzyme.

Food Interaction

May exacerbate adverse effects w/ alcohol.

Action

Description:
Mechanism of Action: Peppermint oil is an aromatic carminative that exerts its effect locally rather than systemically. It causes colonic relaxation and decreases intra-colonic pressure by interfering w/ the mobilisation of Ca ions.

Storage

Store below 25°C.

MIMS Class

Antispasmodics / Other Dermatologicals / Topical Antihistamines/Antipruritics

References

Anti Itch Balm Peppermint Oil Ointment (US Organic Group Corp). DailyMed. Source: U.S. National Library of Medicine. https://dailymed.nlm.nih.gov/dailymed/. Accessed 05/10/2017.

Buckingham R (ed). Peppermint Leaf. Martindale: The Complete Drug Reference [online]. London. Pharmaceutical Press. https://www.medicinescomplete.com. Accessed 03/11/2017.

Dr Tans Pain Relieving 3 Day Herbal Patch Peppermint Patch (Great Loong LLC). DailyMed. Source: U.S. National Library of Medicine. https://dailymed.nlm.nih.gov/dailymed/. Accessed 05/10/2017.

Joint Formulary Committee. Peppermint Oil. British National Formulary [online]. London. BMJ Group and Pharmaceutical Press. https://www.medicinescomplete.com. Accessed 05/10/2017.

Disclaimer: This information is independently developed by MIMS based on Peppermint oil from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2024 MIMS. All rights reserved. Powered by MIMS.com